Table 4. Comparison of the analytical performances of homogeneous assays for LDL-C and HDL-C between fasting and postprandial samples of non-diseased and diseased groups.
| Group | Non-diseased group | Diseased group | ||||||
|---|---|---|---|---|---|---|---|---|
| (fasting, n = 16/postprandial, n = 43) |
(fasting, n = 66/postprandial, n = 43) |
|||||||
| Manufacturer | A | B | C | D | A | B | C | D |
| LDL-Cha | ||||||||
| Mean bias (%) | −1.82/0.21 | −0.95/2.09 | 1.63/2.57 | 1.90/2.55 | 0.03/2.88 | −0.29/3.13 | 4.57/4.16 | 1.25/3.71 |
| TEcom (%) | 3.80/2.18 | 2.89/4.03 | 4.45/5.40 | 3.79/4.44 | 2.00/4.85 | 2.24/5.07 | 7.39/6.99 | 3.14/5.60 |
| CVe (%) | 0.60/0.56 | 0.58/0.57 | 0.54/0.50 | 0.52/0.47 | 0.67/0.72 | 0.48/0.64 | 0.60/0.62 | 0.46/0.61 |
| CVd (%) | 3.92/3.30 | 3.11/3.03 | 2.80/3.42 | 3.97/2.36 | 4.90/6.01 | 5.58/5.16 | 5.92/6.73 | 4.37/5.55 |
|
3.97/3.36 | 3.17/3.09 | 2.86/3.47 | 4.01/2.42 | 4.95/6.06 | 5.61/5.20 | 5.96/6.76 | 4.40/5.59 |
| Mean bias [ECA] (%) | 0.02/−0.44 | 0.51/0.32 | 0.55/0.36 | 0.46/−0.24 | 0.62/−0.07 | 0.88/0.91 | 0.72/0.20 | 0.67/−0.14 |
| TEeca (%) | 7.80/7.03 | 6.72/6.38 | 6.16/7.16 | 8.32/4.98 | 10.32/11.94 | 11.88/11.10 | 12.40/13.45 | 9.29/11.10 |
| HDL-Cha | ||||||||
| Mean bias (%) | 1.78/2.79 | −3.07/−2.99 | −1.59/−1.38 | 1.23/0.65 | 4.10/5.74 | −1.15/−2.21 | 0.94/−0.27 | 0.83/0.12 |
| TEcom (%) | 3.96/5.27 | 4.57/4.49 | 4.07/3.87 | 3.76/3.17 | 6.58/8.22 | 2.65/3.71 | 3.43/2.76 | 4.35/2.65 |
| CVe (%) | 0.61/0.62 | 0.49/0.65 | 0.50/0.65 | 0.58/0.60 | 0.64/0.74 | 0.57/0.61 | 0.75/0.64 | 0.57/0.72 |
| CVd (%) | 3.40/2.47 | 2.57/2.21 | 3.29/3.58 | 2.98/3.23 | 3.69/4.64 | 6.04/3.21 | 4.79/3.74 | 3.93/4.14 |
|
3.46/2.56 | 2.62/2.31 | 3.34/3.65 | 3.04/3.30 | 3.75/4.70 | 6.07/3.27 | 4.85/3.81 | 3.98/4.21 |
| Mean bias [ECA] (%) | 0.72/0.33 | −0.31/−0.39 | 0.17/0.26 | −0.73/−0.78 | 1.43/1.04 | −0.09/0.27 | 0.00/0.47 | −0.55/−0.31 |
| TEeca (%) | 7.50/5.35 | 5.45/4.92 | 6.72/7.41 | 6.69/7.25 | 8.78/10.25 | 11.99/6.68 | 9.51/7.94 | 8.35/8.56 |
LDL-C, low-density lipoprotein-cholesterol; CV, coefficient of variance; HDL-C, high-density lipoprotein-cholesterol; HA, homogeneous assay
Data in each cell are the calculated values for fasting (left) and postprandial (right) samples.
All parameters were calculated as described in the legend to Table 3.
A, Denka Seiken; B, Wako; C, Kyowa Medex; D, Sekisui Medical