(A) Representative MR images of mice: naive, 5 weeks after degenerative cervical myelopathy (DCM), and 5 weeks after surgical decompression (DCM-E + Dec). (B) At 1 week before surgical decompression, the DCM group had a 32% compression ratio, which was significantly reduced to 14.4% in the DCM-E + Dec group (n = 5 animals per group). *P < 0.05, Mann-Whitney U test. (C) Representative MR images of mice: naive, DCM (at 11 weeks after DCM), and DCM-D + Dec (at 5 weeks after surgical decompression). (D) At 1 week before surgical decompression, the DCM group had a 47% compression ratio, which was reduced to 12.8% at 5 weeks after decompression in the DCM-D + Dec group (n = 5 per group). *P < 0.05, Mann-Whitney U test. Compression ratio was calculated based on Fehlings et al. (76), and the data are presented as mean ± SEM.