Table 1.
Observed thermodynamic values from the ITC titration of Fe2+ acetate into TauD
| 25 mM Buffer (pH 7.4) | n | K | ΔHobs (kcal/mol) | ΔHionization (kcal/mol) | ΔG (kcal/mol) | −TΔSobs (kcal/mol) | KFe-buffer |
|---|---|---|---|---|---|---|---|
| MOPS | 0.78 (± 0.13) | 5.4 (± 0.7) × 105 | −2.2 (± 0.3) | −5.04 | −7.8 (± 0.1) | −5.7 (± 0.4) | 42.0 (± 5) |
| HEPES | 0.85 (± 0.13) | 3.3 (± 0.6) × 105 | −1.9 (± 0.5) | −4.86 | −7.5 (± 0.1) | −5.6 (± 0.4) | 72.5 (± 14) |
| ACES | 0.94 (± 0.07) | 1.0 (± 0.7) × 107 | −3.9 (± 0.8) | −7.27 | −9.2 (± 1.0) | −5.3(± 1.5) | 19.7 (± 13) |
Values are the average of 2–4 replicates and the errors associated with the values are one standard deviation from the mean.