Table 3.

Three-way interaction of MAOA genotype x prenatal stress exposure x sex on disruptive behavior in preschoolers ^a (N = 285)

	B	SE	β	95% CI	t	Sig.
Child age	−.296	.239	−.086	−.768 − .176	−1.237	.218
Sex b	.609	.419	.323	−.220 − 1.437	1.451	.149
MAOA genotype c	.355	.187	.189	−.013 − .724	1.902	.059
Prenatal stress exposure (PSE) d	.035	.050	.213	−.065 − .135	.694	.489
Prenatal tobacco exposure e	.041	.032	.094	−.023 − .104	1.264	.208
Prenatal alcohol exposure f	1.881	1.156	.112	−.402–4.163	1.627	.106
Parent antisocial behavior g	.005	.018	.024	−.029 − .040	.306	.760
Concurrent stress exposure h	.047	.013	.310	.020 − .073	3.474	.001
Concurrent tobacco exposure i	.011	.011	.081	−.010 − .033	1.045	.297
Maternal responsiveness	−.001	.040	−.002	−.079 − .077	−.032	.975
MAOA x sex	−.220	.268	−.202	−.749 − .309	−.822	.412
MAOA x PSE	−.212	.216	−.335	−.638 − .215	−.981	.328
PSE x sex	−.797	.426	−.587	−.1.638 − .045	−1.870	.063
MAOA x PSE x sex	.664	.287	.813	.096–1.231	2.309	.022

^aMultidimensional Assessment Profile of Preschool Disruptive Behavior, unidimensional IRT score

^bBoys coded as 1; girls coded as 0

^cChild MAOA genotype (MAOA-L = 1; MAOA-H = 2)

^dLife Stressors and Social Resources Scale (LISRES) assessed at 28 weeks gestation, factor score

^eMean maternal cotinine during pregnancy, natural log-transformed

^fMean reported drinks per day during pregnancy

^gAntisocial behavior questionnaire, sum of maternal and paternal scores

^hLife Stressors and Social Resources Scale (LISRES) assessed at child age 5, factor score

ⁱMaternal smoking in cigarettes/day at child age 5

^jEarly Childhood Home Observation for Measurement of the Environment , responsivity subscale