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Mesalamine increases fecal IgA production. (A) WT (n = 6 mice per group) and AhR-/- mice (n = 4 mice per group), or (B) bone marrow chimeric mice (BM-AhR+/+ mice and BM-AhR-/- mice) (n = 10 mice per group) were orally treated with 50 mg/kg of mesalamine for 2 weeks. Concentrations of IgA of stool samples were measured by ELISA. Error bars represent mean ± SEM. *P < .05. 5-ASA, mesalamine.
