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. 2017 Jun 1;7:2592. doi: 10.1038/s41598-017-03008-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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DLPI Impactor-collected data showing the impact of the PG/VG ratio on the frequency mass distribution. Mass of nicotine is in grey (expressed in %) mass of refill liquid in black (expressed in %). The 80PG/20VG formulation was plotted with continuous lines. The 20PG/80VG formulation was plotted with dotted lines. Experiments were performed in triplicate with a power level fixed at 15 W, a dilution ratio of 1.5 and a same volume of aerosol collected into the cascade impactor for all experimental conditions.