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. 2017 Jun 1;7:2675. doi: 10.1038/s41598-017-02860-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of distributions of d _S (a) and d _N /d _S (b) between expression-unaffected and -affected duplicates of each of the four categories with CG-only methylation due to loss of BCGM. The Kolmogorov-Smirnov test was conducted for statistical significance. There were no significant changes in d _S distribution for any duplication category (K-S test, p values > 0.05), but the ranges of d _N /d _S distribution were significantly larger in expression-unaffected duplicates than expression-affected duplicates (K-S test, p values < 0.01) in the WGD and transposed duplicates.