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. 2017 Jun 1;7:2593. doi: 10.1038/s41598-017-02464-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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UROPA graphical summary report. (A) The distance to the feature anchor is displayed as a fraction of the total peaks annotated using a density plot. This information can be useful to determine optimal distance settings for annotation. (B) Relative localization of peaks in relation to the annotated feature (one pie chart plot per feature). (C) Bar plot of total occurrence of individual features (one plot per query). (D) All queries are included in a pairwise comparison to show possible overlaps. Assuming multiple concurrent queries, the amount of exclusively and commonly annotated peaks can be deduced. (E) Distance histogram in relation to query and feature where each query is depicted separately. (F) The Chow Ruskey plot represents an area-proportional Venn diagram. It reveals the distribution of peaks that could be annotated per query and works for up to 5 queries.