Table 2.

Leukocytosis-promoting and islet-activating activity.

Injected toxin	Dose (μg/mouse)	WBC* ± SEM (102/μl)	Insulin secretion (ng/ml) ± SEM
ArtAB-DT104	0.02	27.8 ± 9.75	0.46 ± 0.11
	0.1	18.0 ± 2.12	0.65 ± 0.18
	0.2	25.5 ± 2.60	0.49 ± 0.11
	0.3	21.0 ± 3.70	1.81 ± 0.30**
ArtAB-SW	0.66	17.3 ± 2.82	2.07 ± 0.66**
ArtAB-Sb	4.13	30.7 ± 7.43	0.89 ± 0.20
PBS	—	34.5 ± 8.15	0.39 ± 0.07

*WBC, peripheral white blood cells. **P < 0.05, one-way analysis of variance and Dunnett’s test.