Table 1.
DLS analysis of FLp53 aggregation
Mean Rh and polydispersity values corresponding to the mean hydrodynamic radius of all components present in the full-length p53 (Flp53) samples acquired at the end point of each aggregation (kinetics) reaction presented in Fig 8.
| Sample | Hydrodynamic radius, Rh | Polydispersity |
|---|---|---|
| nm | % | |
| Aggregated Flp53 Sample | 116.94 ± 9.14 | 18.8 ± 8.7 |
| Flp53 + DHFR RNA (50:1) | 251.68 ± 18.94 | Multimodal |
| Flp53 + DHFR RNA (3:1) | 270.41 ± 130.03 | Multimodal |
| Flp53 + DomV RNA (50:1) | 310.27 ± 19.42 | Multimodal |
| Flp53 + DomV RNA (8:1) | 270.16 ± 4.02 | Multimodal |