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Independently transcribed snoRNA have a distinct chromatin signature. Normalized read depth in a 2 kb region centred on the snoRNA gene start, and oriented in the direction of transcription, is shown for selected independently transcribed snoRNA for RNA polymerase II (a) and for H3K4me3 ChIP sequencing data (b) at seven time points (data from [16]). A peak in PolII over the gene and an adjacent peak in H3K4me3 are characteristic chromatin features.
