Figure 4. Applications of the integral parameter.

(a) The stability curves of Sac7d (continuous line) and Metmyoglobin (dotted line) are characterized by very different values of ΔC_p. (b) The stability curves of lysozyme in glycine buffer at pH 2.0 (dotted line) and in the same buffer with the addition of 5% v/v propanol (PrOH, continuous line). The curves were calculated from the thermodynamic data reported in McCrary et al.³⁶ and in Velicelebi and Sturtevant³⁷ for (a,b), respectively. (c) Plot of relative values of ΔG (squares) for selected hyperthermophile proteins³⁸. (d) Plot of the relative integrals (circles) for the same proteins of c.