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. 2017 Jun 2;4(3):ENEURO.0116-17.2017. doi: 10.1523/ENEURO.0116-17.2017

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Copyright © 2017 Haj-Dahmane et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 1. — Pairing presynaptic stimulation with bAPs induces tLTP of AMPAR-EPSCs. A, Stimulation protocol (left) and voltage response (right) used to induce tLTP. B, Summary graph of the time course and the magnitude of the potentiation of AMPAR-EPSCs induced by pairing presynaptic stimulations with bAPs (•, n = 26), presynaptic stimulation alone (O, n = 10), and bAPs (□, n = 10). Right graph illustrates averaged AMPAR-EPSC traces taken at the time point indicated in the left graph. Note that the induction of the LTP requires pairing of pre- and postsynaptic stimulations.