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. 2017 May 19;8:15242. doi: 10.1038/ncomms15242

Figure 4. Anticoagulant activity of BCN-peg6-OH (9) and in vitro-clicked product (10).

Figure 4

PT values were determined for different compounds following two IP or SC injections with a 24-h interval, as follows: (a) vehicle IP injections to establish control group of mice, n=4. (b) WN3 2 IP injections (2 mg kg−1, n=7). (c) BCN-peg6-OH 9 IP injections (26 mg kg−1 (10 eq), n=4). (d) BCN-peg6-OH 9 SC injections (26 mg kg−1 (10 eq), n=4). (e) BCN-peg6-OH 9 SC injections (52 mg kg−1 (20 eq), n=4). (f) Clicked product 10 IP injections (4.6 mg kg−1 (1 eq), n=4). *P<0.1, PLSD Fisher comparison with vehicle-treated mice. Error bars indicate s.e.m. values.