Table 4. Over-represented motifs identified by MEME^a.

Motifs	Consensus	Frequency (%)	TF	E-value
1	GSGDGSMWGRGGSRGGRS	95	MZF1	2.2E−088
2	VSSYYYMCYCYCKCCHRS	100	SP1	6.9E−041
3	YCYRSSYYCCSGSYYC	100	AP2	5.3E−019
4	CCCYKCCYCHBSCYCSCB	100	GKLF	3.2E−089
5	CCCCGCCCCCCCCCCTCC	100	GC-signal	1.2E−030
6	KYCRCCAKGTTGGTCAGG	24	ERE half-site	1.9E−009
7	GRSCRSCDSCHBBYCC	61	novel	1.8E−002
8	SSSSGSGKYSGSKSSSGS	72	E2F	1.4E−016
9	KRSRGRGRSMSVGGCDG	66	ZF5	2.4E−007
10	YVMKKBBMCYSCYKYDSY	39	novel	2.6E−005

^aThe motifs identified by MEME program on a basis of a dataset which consists of 35 experimentally confirmed ERα targets and 42 ERα target candidates from ChIP-on-chip.