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Functional classification of C-fiber nociceptors from control and Nav1.8-ChR2+ mice (OP+ and OP− nociceptors)
| Group | Fiber Type* | Number | Percent |
|---|---|---|---|
| Control | CM | 14 | 39 |
| CMC | 10 | 28 | |
| CMH | 3 | 8 | |
| CMHC | 9 | 25 | |
| Nav1.8-ChR2+ (OP+) | CM | 10 | 23 |
| CMC | 9 | 20 | |
| CMH | 13 | 30 | |
| CMHC | 11 | 25 | |
| CH | 1 | 2 | |
| Nav1.8-ChR2+ (OP−) | CM | 9 | 100 |
C-fiber nociceptors are classified by temperature sensitivity:
CM, C-mechanonociceptors; CMC, C-mechanocold nociceptors; CMH, C-mechanoheat nociceptors; CMHC, C-mechanoheatcold nociceptors.
