Skip to main content
. 2017 Apr 12;58(6):1080–1090. doi: 10.1194/jlr.M072587

Fig. 1.

Fig. 1.

Effects of DHA metabolites, via LOX, on NRLP3 inflammasome formation in podocytes. Podocytes were cultured for 24 h with Hcys (40 μM) in the absence or presence of 17S-HDHA (17HDHA; 100 nM), RvD1 (60 nM), or DHA (20 μM) as indicated. A: Representative images and summarized data of the colocalization between NLRP3 (green) and ASC (red) in different podocytes, which were cultured and treated on different days (n = 6). B: Representative images and summarized data of the colocalization between NLRP3 (green) and caspase-1 (red) in different podocytes which were cultured and treated on different days (n = 6). *P < 0.05 versus Ctrl-Vehl group, #P < 0.05 versus Hcys-Vehl group. Ctrl, control; Vehl, vehicle; 17S-HDHA, 17-hydroxy docosahexaenoic acid; DHA, ω-3 fatty acid docosahexaenoic acid.