Fig. 4.

Classification of human and rodent FBAs according to their bactericidal activities. See Table 1 for the abbreviated names of the FBAs. “Viability loss-inducing concentration (mM)” was defined as the FBA concentration that caused a reduction in viability to <20% of that of the untreated cells. The asterisk indicates that the bactericidal activities of UCA were not tested at concentrations above 6 mM (Table 2), but were predicted to be above 6 mM from their extremely high hydrophilicities (Table 1) and the decreasing internal pH profiles (Fig. 1).