TABLE 3.
Percent difference in the concentration of HDL with and without apoC-III by lifestyle factors and medication intake in participants of the Danish Diet Cancer and Health study
| Age- and Sex-Adjusted Percent Difference (95% CI)a | Multivariable-Adjusted Percent Difference (95% CI)b | |||
| Exposures | HDL Containing apoC-III | HDL Not Containing apoC-III | HDL Containing apoC-III | HDL Not Containing apoC-III |
| Smoking status | ||||
| Former versus never | −0.78 (−5.40, 4.07) | 0.83 (−1.82, 3.56) | −2.06 (−6.89, 3.02) | 2.08 (−0.77, 5.00) |
| Light (<15 g/day) versus never | −1.67 (−7.09, 4.08) | −0.05 (−3.17, 3.18) | −1.37 (−6.89, 4.77) | 0.19 (−3.13, 3.62) |
| Moderate (15–25 g/day) versus never | −1.67 (−7.09, 4.08) | −2.06 (−4.80, 0.76) | −0.32 (−5.67, 5.34) | −2.36 (−5.32, 0.69) |
| Heavy (≥25 g/day) versus never | −2.78 (−8.77, 3.59) | −0.95 (−4.40, 2.64) | −4.69 (−11.11, 2.20) | −0.83 (−4.62, 3.12) |
| Alcohol consumption (per 15 g/day) | 0.43 (−0.76, 1.63) | 1.42 (0.75, 2.10) | 0.58 (−0.72, 1.90) | 1.58 (0.84, 2.32) |
| Mediterranean diet scorec | ||||
| Medium (3–4) versus low (0–2) | −1.28 (−5.14, 2.75) | −0.45 (−2.65, 1.80) | −1.15 (−5.36, 3.25) | −1.09 (−3.47, 1.34) |
| High (5–8) versus low (0–2) | 0.07 (−4.54, 4.91) | −0.89 (−3.48, 1.77) | −0.17 (−5.24, 5.17) | −1.93 (−4.74, 0.96) |
| Medication intake | ||||
| Hormone therapy use | −1.96 (−9.69, 6.43) | −2.67 (−7.25, 2.13) | 0.17 (−8.39, 9.54) | −3.43 (−8.24, 1.63) |
n = 3,631 except for hormone therapy use (n = 831; postmenopausal women only). Boldface indicates significant result.
Adjusted for age (continuous), sex (male, female), future CHD case status (whether participant developed CHD during 10 year follow-up), and HDL with or without apoC-III concentration, respectively.
Adjusted for age (continuous), sex (male, female), future CHD case status (developed CHD during 10 year follow-up), waist circumference (centimeters), physical activity (continuous), smoking status [never smoker, former smoker, light current smoker (<15 g/day), moderate current smoker (15–25 g/day), heavy current smoker (≥25 g/day)], alcohol consumption (continuous), HDL with or without apoC-III concentration, educational attainment (≤7 years, 8–10 years, >10 years), diabetes medication intake (yes, no), diabetes (yes, no), antihypertensive medication intake (yes vs. no), and hypertension (yes, no).
Additionally adjusted for total caloric intake (continuous).