Table 7. HPRT splice variants characterized in MRC5 by quantitative PCR.

Splice variant	PTC	Splice variant frequency relative to WT frequency in MRC5 (%)	Splice variant frequency relative to WT frequency in emetine-treated MRC5 (%)
Complete exon skipping
2	Yes	0	0
3	Yes	0	0.2 ± 0.3
Exons 2 and 3	No	0.4 ± 0.2	0.6 ± 0.4
4	No	0.2 ± 0.3	0.1 ± 0.3
5	No	0	0
6	Yes	0	0.4 ± 0.5
7	No	0.1 ± 0.3	0.1 ± 0.3
8	No	0.8 ± 0.2	0.7 ± 0.3
Partial exon skipping
4	No	0	0
8	No	0.3 ± 0.5	0.3 ± 0.4
9	Yes	0	0
Partial intron inclusion
1	Yes	N/Da	N/Da
5	Yes	0	0.6 ± 0.3
Complex event
Intron 5 and exon 6	Yes	0	0.1 ± 0.3

^aUnable to determine.