Table 3.

IGFs, IGFBPs and PAPP-A Level (ng/mg of Protein) in Ascites in Patients with Advanced Ovarian Cancer in Ascites Depending on Its Volume, Me (25-75%)

Ascites volume (mL)			Parameters
	IGF-I	IGF-II	IGFBP-3	IGFBP-4	PAPP-A
Low volume (less 200 mL), n=10	1.9 (1.7-2.3)	193.0 (55.0-378.0)	96.9 (88.2-166.0)	5.9 (3.6-12.4)	0.04 (0-0.12)
Moderate volume, n=10	3.9 (0.5-9.5)	165.0 (84.0-281.0)	268.0 (100.0-404.0)	3.6 (0.6-5.6)	0.4 (0.13-0.5)
High volume, n=33	3.0 (1.3-5.0)	67.3 (28.7-124) P1,3<0.05 P2,3<0.05	210.0 (140.0-266.0)	62.3 (51.4-77.8)	0.3 (0.14-0.5) P1,3<0.05 P1,2<0.05

Note, 1,2, changes between protein levels in low- and moderate-volume ascites samples; 1,3, changes between protein levels in low- and high-volume ascites samples; 2,3, changes between protein levels in moderate- and high-volume ascites samples