Table 2.

Comparison of IL-6 Levels in Serum and Saliva

Study Subjects	Serum IL-6 (pg/ml)	Salivary IL-6 (pg/ml)
Healthy Control (n=100)	1.0±0.7	10.8±6.7
Premalignant Lesion subjects (n=50)	25.3±9.9	35.3±14.3
Premalignant Condition subjects (n=50)	25.0±6.3	38.3±12.3
Oral squamous cell carcinoma (n=100)	52.0±19.2	178.0±28.3

The levels of serum and salivary IL-6 were assessed by ELISA in all the study subjects. The concentrations are expressed in picogram per milliliter, and the values represent mean ± SEM.