Table 1.
Demographic, Biochemical Characteristics, Αutoantibodies and IL-6 Level of All Subject
| Patients (n=102) | Control (n=103) | P | |
|---|---|---|---|
| Gender | |||
| Female | 28 (27.5%) | 48.0 (46.6%) | 0.005* |
| Male | 74 (72.5%) | 55.0 (53.4%) | |
| Age | 45.42 ± 10.01 | 28.9 ± 8.4 | <0.001* |
| TLC | 5.35 (2.20 – 33.0) | 5.6 (4.2 – 10.1) | 0.013* |
| Creatinin | 0.90 ± 0.24 | 0.8 ± 0.2 | <0.001* |
| Hemoglobin | 13.06 ± 1.92 | 13.2 ± 0.9 | 0.64 |
| AST | 46.50 (12.0 – 209.0) | 23.0 (10.0 – 40.0) | <0.001* |
| ALT | 51.0 (12.0 – 318.0) | 22.0 (10.0 – 37.0) | <0.001* |
| Alb | 4.22 ± 0.61 | 4.45 ± 0.30 | 0.001* |
| Platelet | 210.54 ± 61.03 | 265.22 ± 56.70 | <0.001* |
| TSH | 2.20 (0.03 – 36.49) | 2.0 (0.40 – 4.20) | 0.616 |
| AFP | 3.10 (1.20 – 2109.0) | 2.0 (0.90 – 8.0) | <0.001* |
| ANA | |||
| Less than 1:80 | 78 (76.5%) | 98.0 (95.1%) | <0.001* |
| 1:80 | 18 (17.6%) | 5.0 (4.9%) | |
| 1:160 | 6 (5.9%) | 0.0 (0.0%) | |
| AMA | |||
| Less than 1:20 | 94 (92.2%) | 103.0 (100.0%) | 0.004* |
| 1:20 | 5 (4.9%) | 0.0 (0.0%) | |
| 1:40 | 3 (2.9%) | 0.0 (0.0%) | |
| ASMA | |||
| Less than 1:20 | 85 (83.3%) | 103.0 (100.0%) | <0.001* |
| 1:20 | 13 (12.7%) | 0.0 (0.0%) | |
| 1:40 | 3 (2.9%) | 0.0 (0.0%) | |
| 1:80 | 1 (1.0%) | 0.0 (0.0%) | |
| ARA | |||
| Less than 1:20 | 99 (97.1%) | 103.0 (100.0%) | 0.126 |
| 1:20 | 1 (1.0%) | 0.0 (0.0%) | |
| 1:40 | 2 (2.0%) | 0.0 (0.0%) | |
| ABBA | |||
| Less than Jan-20 | 102 (100.0%) | 103.0 (100.0%) | - |
| 1:20 | 0 (0.0%) | 0.0 (0.0%) | |
| 1:40 | 0 (0.0%) | 0.0 (0.0%) | |
| APCA | |||
| Less than 1:20 | 84 (82.4%) | 103.0 (100.0%) | <0.001* |
| 1:20 | 11 (10.8%) | 0.0 (0.0%) | |
| 1:40 | 6 (5.9%) | 0.0 (0.0%) | |
| 1:80 | 1 (1.0%) | 0.0 (0.0%) | |
| Anti ribosomal ab | |||
| Less than 1:20 | 102 (100.0%) | 103.0 (100.0%) | - |
| 1:20 | 0 (0.0%) | 0.0 (0.0%) | |
| 1:40 | 0 (0.0%) | 0.0 (0.0%) | |
| Anticanalicular Antibody | |||
| Less than 1:20 | 94 (92.2%) | 103.0 (100.0%) | 0.003* |
| 1:20 | 6 (5.9%) | 0.0 (0.0%) | |
| 1:40 | 2 (2.0%) | 0.0 (0.0%) | |
| IL-6 | 29 (4.0 – 1086.0) | 29.3 (3.70 – 139.0) | 0.028* |
Qualitative data were described using number and percent and was compared using Chi square test; while normally quantitative data was expressed in mean ± SD and was compared using student t-test; abnormally distributed data was expressed in median (Min. - Max.) and was compared using Mann Whitney test;
Statistically significant at p ≤ 0.05