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. 2016;17(11):4985–4989. doi: 10.22034/APJCP.2016.17.11.4985

Table 1.

Association of lnc-LAMC2-1:1 rs2147578 and CASC8 rs10505477 T>C Polymorphism and the Risk of ALL

Polymorphism Case n (%) Control n (%) OR (95%CI) p
lnc-LAMC2-1:1 rs2147578
Codominant
CC 10 (9.1) 38 (31.7) 1.0 -
CG 74 (67.3) 65 (54.2) 4.3 (2.0-9.4) <0.001
GG 26 (23.6) 17 (14.1) 5.8 (2.3-14.7) <0.001
Dominant
CC 10 (9.1) 38 (31.7) 1.0 -
CG+GG 100 (90.9) 82 (68.3) 4.6 (2.2-9.9) <0.001
Recessive
CC+CG 84 (76.4) 103 (85.9) 1.0 -
GG 26 (23.6) 17 (14.1) 1.9 (0.9-3.7) 0.089
Overdominant
CC+GG 36 (32.7) 55 (45.8) 1 -
CG 74 (67.3) 65 (54.2) 1.7 (1.0-3.0) 0.044
Allele
C 94 (42.7) 141 (58.7) 1.0 -
G 126 (57.3) 99 (41.3) 1.9 (1.3-2.8) <0.001
CASC8 rs10505477 T>C
Codominant
TT 40 (36.4) 35 (29.2) 1.0 -
TC 43 (39.1) 56 (46.6) 0.7 (0.4-1.2) 0.222
CC 27 (24.5) 29 (24.2) 0.8 (0.4-1.6) 0.599
Dominant
TT 40 (36.4) 35 (29.2) 1.0 -
TC+CC 70 (63.6) 85 (70.8) 0.7 (0.4-1.2) 0.265
Recessive
TT+TC 83 (75.5) 91 (75.8) 1.0 -
CC 27 (24.5) 29 (24.2) 1.0 (0.6-1.9) 0.976
Overdominant
TT+CC 67 (60.9) 64 (53.4) 1.0 -
TC 43 (39.1) 56 (46.6) 0.7 (0.4-1.2) 0.287
Allele
T 123 (60.4) 126 (52.5) 1.0 -
C 97 (39.6) 114 (47.5) 0.9 (0.6-1.3) 0.512