Table 1.

The General Characteristics of Eligible 27 Studies

Studies	Region	Assay	Cut off	SCLC	Control	TP	FP	FN	TN
Zeng 2016	China	ECLIA	73.5	31	131	23	7	8	124
Li 2003	China	ELISA	40.0	30	60	22	1	8	59
Shi 2005	China	ELISA	NR	45	125	35	50	10	75
Yang(a) 2000	China	ELISA	40.0	30	60	22	1	8	59
Yang(b) 2005	China	ELISA	46.0	63	81	46	9	17	72
Zhang 2009	China	ELISA	46.0	83	125	60	3	23	122
Wang 2010	China	ELISA	50	21	115	14	2	7	113
Yoshio 1994	Japan	RIA	NR	140	658	107	14	33	644
Ken 1995	Japan	ELISA	50.0	127	351	80	4	47	347
Katsumi 1995	Japan	ELISA	45.1	25	287	18	2	7	285
Takada 1996	Japan	ELISA	33.8	101	114	63	6	38	108
Takuji 1997	Japan	ELISA	46.0	44	77	31	7	13	70
Koichi 1997	Japan	ELISA	46.0	206	544	140	23	66	521
Stieber 1999	Japan	ELISA	38.3	87	74	41	4	46	70
Sunaga 1999	Japan	ELISA	46.0	48	79	36	5	12	74
Shibayama 2000	Japan	ELISA	49.0	114	142	74	5	40	137
Oremek(a) 2003	Germany	ELISA	87.0	80	129	80	67	0	62
Oremek(b) 2007	Germany	SLT-S	87.0	80	209	67	10	13	199
Stefan 2010	Germany	ELISA	NR	53	128	32	6	21	122
Bijan 2013	Germany	EIA	101.0	50	90	50	4	0	86
Molina(a) 2004	Spain	ELISA	50.0	41	122	32	32	9	90
Molina(b) 2005	Spain	ELISA	50.0	73	568	47	93	26	475
Molina(c) 2009	Spain	ELISA	50.0	175	627	134	79	41	548
Lamy 2000	France	ELISA	53.0	146	59	117	2	29	57
Nisman 2009	Israel	ELISA	48.0	37	88	28	2	9	86
Wojcik 2008	Poland	ELISA	49.0	83	34	68	3	15	31
Marianne 2012	Norway	ELISA	330	49	129	40	6	9	123

ECLIA, electrochemiluminescence assays; RIA, radioimmunoassay; SLT-S, SLT-Spectra photometer; EIA, enzyme-immunological assay; NR, not reported.