Table 2.
Results of Meta-Analysis for XRCC3 rs861539 Polymorphism and OSA Risk
| Genetic model | No. study | Type of model | Heterogeneity | Odds ratio | Publication Bias | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| I2 (%) | PH | OR | 95% CI | POR | PBeggs | PEggers | ||||
| Pooled | ||||||||||
| T vs. C | 2 | Fixed | 0 | 0.848 | 1.563 | 1.244-1.963 | <0.001 | NA | NA | |
| TC vs. CC | 2 | Fixed | 0 | 0.971 | 1.361 | 0.982-1.885 | 0.064 | NA | NA | |
| TT vs. CC | 2 | Fixed | 0 | 0.917 | 2.574 | 1.573-4.212 | <0.001 | NA | NA | |
| TT+TC vs. CC | 4 | Fixed | 58.12 | 0.067 | 1.255 | 1.011-1.558 | 0.039 | 0.308 | 0.529 | |
| TT vs. TC+CC | 2 | Fixed | 0 | 0.909 | 2.224 | 1.393-3.552 | 0.001 | NA | NA | |
| Caucasian | ||||||||||
| TT+TC vs. CC | 1 | Fixed | 0 | 1 | 0.713 | 0.438-1.161 | 0.174 | NA | NA | |
| Asian | ||||||||||
| TT+TC vs. CC | 3 | Fixed | 0 | 0.697 | 1.442 | 1.133-1.835 | 0.003 | 1 | 0.612 | |