Table 3.
Twin correlations and heritability estimates (with 95% confidence intervals) for longitudinal measures of No-Go and Go ERP components.
| ERP phenotype | Age | rMZ | rDZ | Additive Genetic (Heritability) | Non-shared Environmental |
|---|---|---|---|---|---|
| N2, FCZ | 12 | 0.60* (0.49 – 0.69) | 0.33* (0.19 – 0.45) | 0.62* (0.53 – 0.69) | 0.38* (0.31 – 0.47) |
| 14 | 0.56* (0.43 – 0.66) | 0.26* (0.10 – 0.40) | 0.56* (0.45 – 0.65) | 0.44* (0.35 – 0.55) | |
| 16 | 0.52* (0.30 – 0.69) | 0.08 (−0.14 – 0.29) | 0.49* (0.33 – 0.63) | 0.51* (0.37 – 0.67) | |
| P3N, FCZ | 12 | 0.60* (0.48 – 0.69) | 0.28* (0.13 – 0.41) | 0.60* (0.50 – 0.68) | 0.40* (0.32 – 0.50) |
| 14 | 0.55* (0.42 – 0.65) | 0.32* (0.17 – 0.46) | 0.58* (0.47 – 0.67) | 0.42* (0.34 – 0.53) | |
| 16 | 0.64* (0.46 – 0.77) | 0.06 (−0.16 – 0.27) | 0.61* (0.45 – 0.73) | 0.39* (0.27 – 0.55) | |
| P3G, PZ | 12 | 0.60* (0.49 – 0.69) | 0.28* (0.13 – 0.41) | 0.62* (0.53 – 0.69) | 0.38* (0.31 – 0.47) |
| 14 | 0.66* (0.55 – 0.74) | 0.21* (0.06 – 0.37) | 0.63* (0.53 – 0.71) | 0.37* (0.29 – 0.47) | |
| 16 | 0.66* (0.47 – 0.78) | 0.22 (−0.00 – 0.42) | 0.63* (0.48 – 0.74) | 0.37* (0.26 – 0.52) |
N2, FCZ: amplitude of the No-Go N2 component at the fronto-central midline electrode (FCz); P3N, FCZ: amplitude of the No-Go P3 component at FCz; P3G, PZ: amplitude of the Go P3 component at the parietal midline electrode (Pz). rMZ and rDZ are intrapair correlations for MZ and DZ twin pairs, respectively (95% confidence intervals are shown in brackets);
p<.05;
a2 is the proportion of total phenotypic variance explained by genetic factors (heritability) and e2 is the proportion of variance due to non-shared environmental factors. Variance component estimates are based on the best-fitting model (see text and Supplementary Table 1).