Figure 2.

Deconvoluted electrospray ionization mass spectra (ESI-MS) of Arsenic-MT species (As_0-3-α-MT-1a) covalently modified by p-benzoquinone (Bq). (A) Metal-free protein; (B) Partially metalated α-MT with As(III) with a large fraction of apo-protein; (C) Species in 1B fully modified by excess Bq; (D) Partially metalated α-MT with a larger fraction of saturated As₃-α-MT; (E) Addition of 2 mol eq. of Bq to the species in 1D; (F) Species in 1D fully modified by excess Bq. Reproduced with permission from Irvine et al., 2013 [87].