Figure 4.
(A) Food intake per 4 h and food intake per light/dark cycle of Ghr-RVTA mice (+) and Ghr-R knockout (KO) control mice (−) after 7–10 days in the indirect calorimetry cages after habituation as a measure of baseline values; (B–D) Respiratory exchange ratio (RER) values, oxygen consumption, and locomotor activity measurements during the same time period. * p ≤ 0.05, ** p ≤ 0.01, n = 7–8. All data are expressed as mean ± SEM. The stars depicted in the top of the graphs showing development over time indicate the main effects in a repeated-measures two-way ANOVA, whereas the stars depicted directly above the time points indicate the significance for the given time point when tested post hoc by applying Fisher’s LSD test.