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Effect of hypoxia on EGFR downstream signaling in HNSCC cell lines. Western blot analysis of the EGFR signaling pathway in LK042 and UT-SCC-14 HNSCC cells treated with 60 nM of cetuximab for 3 days; GAPDH was used as the loading control. Abbreviations: N, normoxia; N + Cx, normoxia in the presence of cetuximab; H, hypoxia; H + Cx, hypoxia in the presence of cetuximab; Cx, cetuximab.
