Table 5.
Cox proportional hazards regression of all-cause mortality on baseline galectin-3 (Gal-3) levels for all AS patients irrespective of type of treatment employed.
Predictor Variable | β ± SEM | Hazard Ratio (HR) | |
---|---|---|---|
Mean HR (95% CI) | p | ||
Gal-3, unadjusted | |||
Gal-3 (Gal-3 >17.8 vs. <17.8 ng/mL) | 0.71 ± 0.43 | 2.03 (0.88–4.69) | 0.09 |
Gal-3 (per 1-SD increment) | 0.40 ± 0.20 | 1.49 (1.00–2.21) | 0.05 |
Gal-3, adjusted for eGFR | |||
Gal-3 (Gal-3 >17.8 vs. <17.8 ng/mL) | 0.53 ± 0.52 | 1.70 (0.61–4.73) | 0.31 |
Gal-3 (per 1-SD increment) | 0.38 ± 0.29 | 1.46 (0.83–2.57) | 0.19 |
Abbreviations: AS: aortic stenosis; β: regression coefficient; CI: confidence interval; eGFR: estimated glomerular filtration rate; SD: standard deviation; SEM: standard error of the mean.