Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Global loss of DNA methylation in cancer cells leads to TE reactivation. A common epigenetic feature in neoplastic cells is global demethylation, including within repeated sequences. Subsequently, TE reactivation can cause increasing somatic retrotransposition, non-coding RNA, and transcriptional deregulation. Red arrows show direct impacts of TE reactivation and black arrows show effects of retrotransposition.
