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. 2017 May 5;18(5):983. doi: 10.3390/ijms18050983

Table 1.

The application of genomics in lactation research in dairy cows.

Methodology Sample Source Candidate Genes/Biomarker References
Milk production
A combination of mapping and molecular approaches Cattle whole genome shotgun (WGS) downloaded from National Center for Biotechnology Information The ras-related protein rap-1A on bovine chromosome 3, insulin-like growth factor 2 [12,13]
Milk composition
Bayesian stochastic search variable selection model Milk Diacylglycerol-acyl transferase 1 (DGAT1), DGAT1 K232A, stearoyl CoA desaturase 1 A293 V polymorphisms, sterol response element-binding protein-1 [14,15,16]
Animal model in ASReml or capillary zone electrophoresis Milk β-casein (CN) genotype and the κ-CN genotype, variants of the β-lactoglobulin (LG) genotype B and the β-κ-CN haplotype A2B [17,18]
Mastitis
Genome-wide association studies Blood SNPs on Bos Taurus autosome 4 (BTA4), BTA18, and BTA6 [19]