α-GalCer	α-Galactosylceramide
AIH	Autoimmune hepatitis
ALF	Acute liver failure
APAF-1	Apoptotic peptidase activating factor-1
APAP	Acetaminophen
AQ	Amodiaquine
ASK1	Apoptosis signal regulating kinase 1
ATG	Autophagy
ATP	Adenosine triphosphate
Bax	Bcl-2-like protein 4
Bcl-2	B-cell lymphoma 2
c-FLIP	FLICE inhibitory protein
CD4	Cluster of differentiation 4
CD8	Cluster of differentiation 8
CD95	Cluster of differentiation 95, also known as the FAS receptor
cIAP1/2	Cellular inhibitor of apoptosis 1/2
Con A	Concanavalin A
CTLA4	Cytotoxic T-lymphocyte-associated protein 4
CYP	Cytochrome P450
DILI	Drug-induced liver injury
DILIN	Drug-Induced Liver Injury Network
DNA	Deoxyribonucleic acid
DOK4	Docking protein 4
DR	Death receptors
ER	Endoplasmic reticulum
ETC	Electron transport chain
FADD	Fas-associated protein with death domain
FasL	Fas ligand
Fer-1	Ferrostatins
FLICE	Fas-associating protein with death domain-like interleukin-1 β-converting enzyme
GalN	D-galactosamine
GPX4	Glutathione peroxidase 4
GSDMD	Gasdermin D
GSH	Glutathione
GSK3β	Glycogen synthase kinase 3 β
GST1	Glutathione-S-transferase
GWAS	Genome-wide association studies
HDS	Herbal and dietary supplements
HLA	Human leukocyte antigen
HSC	Hepatic stellate cells
IDILI	Idiosycratic drug-induced liver injury
IFNγ	Interferon γ
IL-10	Interleukin 10
INH	Isoniazide
iNOS	Inducible nitric oxide synthase
iPSC	Induced pluripotent stem cell
JAK	Janus kinase
JNK	c-Jun terminal kinase
KC	Kupffer cells
LPO	Lipid peroxidation
LPS	Lipopolysaccharide
LSECs	Liver sinusoidal endothelial cells
MAPK	Mitogen-activated protein kinases
MHC	Major histocompatibility complex
MiR	micro RNA
MKK4	Mitogen-activated protein kinase kinase 4
MLK3	Mixed-lineage kinase 3
MLKL	Mixed lineage domain like
MOMP	Mitochondrial outer membrane permeabilization
MPT	Membrane permeability transition
NAPQI	N-acetyl-p-benzoquinoneimine
Nec	Necrostatins
NFκB	Nuclear factor kappa-light-chain-enhancer of activated B cells
NK	Natural killer cells
NKT	Natural killer T cells
NOS	Nitric oxide synthase
NPC	Non-parenchymal cells
PD1	Programmed cell death protein 1
PKCα	Protein kinase C α
PHH	Primary human hepatocytes
PMH	Primary mouse hepatocytes
PTPN6	Protein tyrosine phosphatase type 6
RHIM	RIP homology interaction motif
RIPK1/RIP1	Receptor interacting serine/threonine kinase 1
RIPK3/RIP3	Receptor interacting serine/threonine kinase 3
ROS	Reactive oxygen species
Sab	SH3 binding protein 5
SEB	Super-antigen staphylococcal enterotoxin B
SJS	Stevens–Johnson syndrome
STAT	Signal transducer and activator of transcription
STAT1	Signal transducer and activator of transcription 1
SULT2A1	sulfotransferase 2A1
T-regs	Regulatory T cells
TAB2/3	TAK1-binding protein 2/3
TAK1	Transforming growth factor-β-activated kinase 1
tBid	Cleaved Bid
TCR	T cell receptor
TEN	Toxic epidermal necrosis
TGFβ	Transforming growth factor β
TNF	Tumor necrosis factor
TNFR1	Tumor necrosis factor receptor 1
TNFα	Tumor necrosis factor α
TRADD	TNFR-associated death domain
TRAF2/5	TNFR-associated factor 2/ 5
TRAIL-R1/R2	TNF-related apoptosis-inducing ligand receptor 1/2
UPR	Unfolded protein response
WT	Wild type