Table 2.
Nucleotide sequence identities of VP1 genes between clades and subclades of EV-D68 strains.
| Strains * | Pairwise Identity (%) | Average Nucleotide Divergence (%) [Range] |
|---|---|---|
| Interclade | 10.8 [6.5–14.8] | |
| Prototype vs. A | 87–87.9 | |
| Prototype vs. B | 85.5–86.6 | |
| Prototype vs. C | 87.8–88 | |
| Prototype vs. D | 85.2–86.7 | |
| A vs. B | 86.5–90.4 | |
| A vs. C | 88.8–91.4 | |
| A vs. D | 90.2–93.5 | |
| B vs. C | 89.8–93.1 | |
| B vs. D | 86.4–89.7 | |
| C vs. D | 87.9–90.5 | |
| A vs. D1 | 90.2–91.7 | |
| A vs. D2 | 91.8–93.5 | |
| Intersubclade | 4.7 [2.6–7.1] | |
| B1 vs. B2 | 94–95.2 | |
| B1 vs. B3 | 94.7–97.4 | |
| B2 vs. B3 | 92.9–94.2 | |
| D1 vs. D2 | 94.1–95.6 | |
| Intrasubclade | 1.4 [0–3.5] | |
| B1 | 96.5–99.8 | |
| B2 | 98.9–100 | |
| B3 | 97.3–99.9 | |
| D1 | 97.5–99.7 | |
| D2 | 98.1–99.6 |
* VP1 sequences of the EV-D68 strains used for the analysis are shown in Table A1 in Appendix A.