Table A1.
List of EV-D68 strains used for analysis in the present study.
| Strain | Year of Isolation | Place of Isolation | Clade * | Source | GenBank Accession No. |
|---|---|---|---|---|---|
| Fermon (prototype) | 1962 | USA | Original | GenBank | AY426531 |
| CA/RESP/10-786 | 2013 | USA | A | GenBank | KM892500 |
| NYC403 | 2009 | USA | A | GenBank | JX101846 |
| NZ-2010-541 | 2010 | NZ | A | GenBank | JX070222 |
| HK2/2010 | 2010 | HK | A | GenBank | KT959174 (VP1), |
| KT959114 (2C) | |||||
| TW-02378_2010 | 2010 | TW | A | GenBank | KP657713 (VP1) |
| ITA/19391/12 | 2012 | Italy | A | GenBank | KC763159 (VP1) |
| 2011-21282 | 2011 | China | B1 | GenBank | KT285320 |
| HK8/2011 | 2011 | HK | B1 | GenBank | KT959180 (VP1), |
| KT959120 (2C) | |||||
| HK14/2012 | 2012 | HK | B1 | GenBank | KT959186 (VP1) |
| KT959126 (2C) | |||||
| HK26/2014 | 2014 | HK | B1 | GenBank | KT959198 (VP1), |
| KT959138 (2C) | |||||
| NY316 | 2014 | USA | B1 | GenBank | KP745764 |
| STL_2014_12 | 2014 | USA | B1 | GenBank | KM881710 |
| US/CO/13-60 | 2013 | USA | B1 | GenBank | KP100794 |
| US/CO/14-93 | 2014 | USA | B1 | GenBank | KP126911 |
| US/MO/14-18950 | 2014 | USA | B1 | GenBank | KM851228 |
| NY73 | 2014 | USA | B2 | GenBank | KP745768 |
| NY74 | 2014 | USA | B2 | GenBank | KP745769 |
| US/KY/14-18951 | 2014 | USA | B2 | GenBank | KM851229 |
| US/IL/14-18952 | 2014 | USA | B2 | GenBank | KM851230 |
| 2014-R0672 | 2014 | China | B3 | GenBank | KT280500 |
| Beijing-R0132 | 2014 | China | B3 | GenBank | KP240936 |
| HK25/2014 | 2014 | HK | B3 | GenBank | KT959197 (VP1), |
| KT959137 (2C) | |||||
| HK28/2014 | 2014 | HK | B3 | GenBank | KT959200 (VP1), |
| KT959140 (2C) | |||||
| TW-00932-2014 | 2014 | TW | B3 | GenBank | KT711081 |
| TW-00785-2014 | 2014 | TW | B3 | GenBank | KT711083 |
| NY10_16 | 2016 | USA | B3 | GenBank | KX957754 |
| USA/FL/2016-19504 | 2016 | USA | B3 | GenBank | KX675261 |
| SWE_003_2016 | 2016 | SWE | B3 | GenBank | KY215829 (VP4) |
| SWE_015_2016 | 2016 | SWE | B3 | GenBank | KY215841 (VP4) |
| USA/U2221/2008 | 2008 | USA | C | GenBank | KX255371 |
| USA/MO93/2009 | 2009 | USA | C | GenBank | KX261814 |
| JPOC10-290 | 2010 | Japan | C | GenBank | AB601882 |
| JPOC10-378 | 2010 | Japan | C | GenBank | AB601883 |
| 2011-21286 | 2011 | China | D1 | GenBank | KT306743 |
| 2012-12225 | 2012 | China | D1 | GenBank | KT285319 |
| 2013-1017-26 | 2013 | China | D1 | GenBank | KT280501 |
| HK5/2011 | 2011 | HK | D1 | GenBank | KT959177 (VP1), |
| KT959117 (2C) | |||||
| HK13/2012 | 2012 | HK | D1 | GenBank | KT959185 (VP1), |
| KT959125 (2C) | |||||
| HK21/2013 | 2013 | HK | D1 | GenBank | KT959193 (VP1), |
| KT959133 (2C) | |||||
| US/KY/14-18953 | 2014 | USA | D1 | GenBank | KM851231 |
| TW-02722_2013 | 2013 | TW | D1 | GenBank | KP657720 (VP1) |
| BCH895A | 2008 | China | D2 | GenBank | KF726085 |
| BJ24 | 2008 | China | D2 | GenBank | KU242683 |
| 1737-Yamagata-2008 | 2008 | Japan | D2 | GenBank | AB667899 (VP1) |
| TW-01166_2007 | 2007 | TW | D2 | GenBank | KP657701 (VP1) |
| TW-11134_2009 | 2009 | TW | D2 | GenBank | KP657708 (VP1) |
| V12-2240471 | 2012 | HK | B1 | This study | KY767823 (VP1), |
| KY767829 (5′UTR), | |||||
| KY767836 (2C) | |||||
| V12-2268728 | 2012 | HK | B1 | This study | KY767820 |
| V13-2245157 | 2013 | HK | D1 | This study | KY767821 |
| V14-8133616 | 2014 | HK | B3 | This study | KY767824 (VP1), |
| KY767830 (5′UTR), | |||||
| KY767837 (2C) | |||||
| V14-8135150 | 2014 | HK | B3 | This study | KY767825 (VP1), |
| KY767831 (5′UTR), | |||||
| KY767838 (2C) | |||||
| V14-8143594 | 2014 | HK | B3 | This study | KY767826 (VP1), |
| KY767832 (5′UTR), | |||||
| KY767839 (2C) | |||||
| V14-8143833 | 2014 | HK | B3 | This study | KY767827 (VP1), |
| KY767833 (5′UTR), | |||||
| KY767840 (2C) | |||||
| V14-8151518 | 2014 | HK | B3 | This study | KY767828 (VP1), |
| KY767834 (5′UTR), | |||||
| KY767841 (2C) | |||||
| V14-8151546 | 2014 | HK | B3 | This study | KY767822 |
| V14-8157864 | 2014 | HK | B3 # | This study | KY767835 (5′UTR), |
| KY767842 (2C) |
# VP1 sequence not available; partial 5’UTR and 2C were sequenced (100% identical to those of EV-D68 strain V14-8151546; potential subclade B3). Abbreviations: HK, Hong Kong; NZ, New Zealand; SWE, Sweden; TW, Taiwan; USA, the United States of America.