Table 3.
Antimicrobial and cytotoxic activities of Ocotea essential oils and some major essential oil components. MIC, minimum inhibitory concentration; IC50, median inhibitory concentration.
| Material | MIC (μg·mL−1) | IC50 (μg·mL−1) | ||||
|---|---|---|---|---|---|---|
| P. aer | E. coli | S. epi | S. aur | B. cer | MCF-7 | |
| Can-L | 1250.0 | 19.5 | 625.0 | 625.0 | 625.0 | 63.9 ± 3.7 |
| Cau-L | 1250.0 | 19.5 | 625.0 | 625.0 | 312.5 | 64.0 ± 3.7 |
| Cuj-L | 1250.0 | 19.5 | 312.5 | 625.0 | 312.5 | 67.7 ± 3.7 |
| α-Pinene | 625 | 312 | - | 312 | 625 | 69.5 ± 1.3 |
| β-Pinene | 1250 | 625 | - | 625 | 312 | 71.2 ± 2.0 |
| Limonene | 1250 | 625 | - | 312 | 625 | 77.4 ± 1.2 |
| β-Caryophyllene | 1250 | 312 | - | 312 | 156 | 59.4 ± 5.1 |
| α-Humulene | 1250 | 625 | - | 312 | 312 | 26.5 ± 5.6 |
| Germacrene D | 1250 | 625 | - | 156 | 625 | 69.6 ± 2.5 |
| Caryophyllene oxide | 1250 | 1250 | - | 1250 | 156 | 73.4 ± 3.7 |
| Gentamicin control | 1.22 | 2.44 | <19.5 | 0.61 | 1.22 | - |
| Tingenone control | <19.5 | <19.5 | - | 2.44 | 1.22 | 16.8 ± 1.7 |
P. aer (Pseudomonas aeruginosa), E. coli (Escherichia coli), S. epi (Staphylococcus epidermidis), S. aur (Staphylococcus aureus), B. cer (Bacillus cereus).