Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CYP450 activity in primary human hepatocytes in response to known inducers and inhibitors of CYP3A4, CYP2B6, and CYP1A2. Aside from ticlopidine, CYP activities were significantly induced and inhibited as expected. In all cases, higher CYP450 activity was observed in 3D than in 2D. ^, #: p < 0.05 effect of concentration on activity. *: p < 0.05 difference in activity between 2D and 3D. Error bars represent standard error.
