Table 3.

Longitudinal study patient cohort identifying gender, disease onset site, riluzole state, age at symptom onset, baseline sample age, and the time between samples

Longitudinal study patient cohort
Gender	Disease onset site	Riluzole naïve	Age at symptom onset (y)	Baseline sample age (y)	Time since diagnosis to baseline sample (mo)	Time since diagnosis to latest sample (mo)
F	Bulbar	Yes	71.4	75.6	0.9	8.3
M	Lower limb	Yes	41.8	43.9	−0.1	13.3
M	Lower limb	Yes	67.5	78.0	0.0	3.3
F	Lower limb	Yes	84.8	85.8	−0.3	11.9
M	Lower limb	Yes	49.7	51.2	−0.2	10.7
M	Bulbar	Yes	70.5	70.9	−1.1	5.9
M	Upper limb	Yes	29.8	31.5	−0.8	10.9
F	Upper limb	Yes	67.2	68.4	−0.2	11.3
M	Lower limb	Yes	40.2	43.1	−0.6	13.0
M	Mixed	Yes	59.2	59.6	−1.2	11.0
M	Mixed	No	59.3	59.9	−0.2	10.1
F	Upper limb	No	63.2	65.8	2.3	14.0
M	Bulbar	No	59.3	59.9	1.4	17.9
M	Lower limb	No	46.5	48.7	1.4	18.3
M	Bulbar	No	56.5	57.1	3.0	10.6
F	Lower limb	No	53.7	57.0	0.0	12.6
M	Lower limb	No	74.2	75.3	1.4	10.5
F	Upper limb	No	77.0	77.8	1.7	7.4
M	Upper limb	No	70.8	71.2	1.4	8.6
M	Bulbar	No	71.8	72.5	1.9	5.5
M	Upper limb	No	30.4	31.9	1.8	8.1
M	Lower limb	Yes	61.1	62.8	−0.3	7.5