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. 2017 Jun 2;17:391. doi: 10.1186/s12885-017-3372-8

Table 3.

Relationship between clinicopathological characteristics and PNI or NLR

Variable N PNI P value NLR P value
Gender 0.068 0.406
 male 436 48.05 (44.95–51.75) 2.39 (1.77–3.47)
 female 80 46.90 (43.87–50.05) 2.21 (1.59–3.97)
Age, years <0.001 <0.001
  > 65 278 46.92 (43.33–49.68) 2.61 (1.95–3.91)
  ≤ 65 238 49.62 (46.25–53.22) 2.15 (1.68–2.92)
Histology type 0.396 0.667
 UC 488 47.80 (44.65–51.55) 2.33 (1.76–3.49)
 NUC 28 48.95 (46.15–53.05) 2.67 (1.66–3.54)
Pathological grade 0.086 0.048
 2 131 48.65 (45.25–52) 2.24 (1.70–2.90)
 3 385 47.65 (44.52–51.15) 2.43 (1.76–3.73)
T stage <0.001 <0.001
 pT2 or greater 354 47.35 (44.05–50.65) 2.52 (1.90–3.93)
 pT1 162 49.00 (46.20–52.97) 2.06 (1.63–2.68)
N status 0.250 0.041
 negative 435 48.00 (44.90–51.65) 2.29 (1.71–3.42)
 positive 81 47.10 (43.87–51.02) 2.50 (1.99–3.96)
Smoking 0.109 0.524
 no 355 47.55 (44.40–51.57) 2.39 (1.72–3.64)
 yes 161 48.70 (45.42–51.60) 2.33 (1.81–3.17)
Diabetes Mellitus 0.948 0.179
 no 460 47.8 (44.75–51.60) 2.32 (1.73–3.44)
 yes 56 48 (44.50–51.28) 2.72 (1.81–3.99)
Hypertension 0.862 0.067
 no 367 47.80 (44.75–51.65) 2.27 (1.71–3.19)
 yes 149 48.02 (44.57–51.15) 2.50 (1.82–3.75)
Heart disease 0.177 0.516
 no 461 47.97 (44.90–51.65) 2.31 (1.73–3.53)
 yes 55 47.22 (43.70–50.56) 2.48 (1.78–3.09)
Cerebrovascular disease 0.277 0.045
 no 499 47.95 (44.71–51.6) 2.32 (1.72–3.44)
 yes 17 47.10 (42.77–49.10) 2.69 (2.22–4.04)
Surgery style 0.278 0.806
 open 409 47.95 (44.9051.75) 2.37 (1.73–3.65)
 laparoscopic 107 47.60 (44.2051.25) 2.28 (1.80–3.20)
Postoperative complications 0.129 0.730
 no 443 48.00 (45.05–51.55) 2.33 (1.76–3.47)
 yes 73 46.35 (43.75–51.78) 2.37 (1.59–3.61)
ASA grade <0.001 0.031
 1&2 436 48.05 (45.25–51.90) 2.30 (1.725–3.21)
 3&4 80 46.00 (42.50–49.37) 2.53 (2.05–3.99)
Anemia <0.001 <0.001
 no 372 49.07 (46.502.93) 2.23 (1.69–2.96)
 yes 144 44.55 (40.90–47.38) 3.01 (2.00–4.42)

UC urothelial carcinoma, NUC non-urothelial carcinoma, ASA American Society of Anesthesiologists, PNI prognostic nutritional index, NLR neutrophil-lymphocyte ratio, PLR platelet-lymphocyte ratio, LMR lymphocyte-monocyte ratio

Significant values are in bold