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. 2005 Jan 7;102(3):904–908. doi: 10.1073/pnas.0408906102

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Fig. 1. — Reduced paw edema in eNOS^-/- mice. (A) eNOS^-/- mice display a reduced edema. Both the first and second phases of the carrageenan-induced edema (n = 6 per group) are influenced. (B) eNOS^-/- mice display a reduction in tissue MPO levels at the 2-h time point (n = 6 per group; C). Data are expressed as mean ± SEM. ^**, P < 0.01; ^***, P < 0.001. (C) Hematoxylin and eosin staining of saline- (Left) and carrageenan-injected (Right) paws. Paws from eNOS^-/- mice show a marked reduction in interstitial edema formation after carrageenan injection compared with paws from injected WT (C57BL/6J) mice.