Table I.
Characteristic | N (%) |
---|---|
Age | |
Median (range) | 59 (49–76) |
Gender | |
Male : Female | 10 : 5 |
Prior therapies | |
Median (range) | 5 (1–14) |
Prior nucleoside analog | 13 (87) |
Prior allogeneic stem cell transplant | 1 (7) |
Cytogenetic abnormalities | |
Normal | 1 (7) |
Trisomy 12 | 1 (7) |
Deletion 11q | 1 (7) |
Deletions 17p | 2 (14) |
Complex | 10 (67) |
Treatment Delivery | |
Dose Level 1 (16 mg/m2) | 5 |
Dose Level 2 (20 mg/m2) | 3 |
Dose Level 3 (24 mg/m2) | 7 |