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. 2017 Jun 1;7:10. doi: 10.1186/s13395-017-0128-8

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — C5aR1 is localised to infiltrating CD11b⁺ macrophages in the tibialis anterior (TA) muscle of wild-type (WT) and hSOD1^G93A (SOD1) transgenic mice. Panels a to h show double immuno-labelling of C5aR1 (red) with cellular marker (green) for macrophages (CD11b; a to c for WT (detailed in d); e to h for SOD1 mice) in the TA muscle of WT and SOD1 mice at end stage disease. C5aR1 was co-localised with CD11b positive macrophages in WT and SOD1 mice (yellow arrows in d and h). Scale bar = 20 μm