Figure 1.

Temporal changes in growth-arrest specific gene (Gas)6 transcript and protein levels in clinical asthma and experimental allergic airway disease. (A) Protein level of Gas6 in plasma from patients with asthma categorized according to disease severity (normal, n = 8; mild, n = 15; moderate, n = 25; severe, n = 26). *P < 0.05 versus the normal control group. (B) Protein level of Gas6 in whole lung samples before and at 3, 7, 14, and 28 days after conidia challenge. Results are expressed as the mean ± SEM for n = 5 per group. Data are representative of two separate experiments. **P < 0.01 versus the naive group. (C) Lung tissue sections from naive and allergic mice were subjected to immunohistochemical analysis for Gas6. Original magnification: ×400.