Plasma cytokine levels after sepsis in WT (sv129 strain) and 5-LO−/− mice. IL-1β, IL-6, IL-10, IL-17, KC, and MCP-1 levels were quantified in plasma 16 hours after sham or CLP in WT and 5-LO−/− mice by ELISA. Data are presented as the mean ± SEM. *P < 0.05 compared with sham group. #P < 0.05 compared with CLP/WT mice.