Table 1. Fusion host range of the syncytin-A and -B envelopes genes.
Fusion efficiency
|
|||||
---|---|---|---|---|---|
Species | Cell | Syncytin-A | Syncytin-B | A-Rless | Control |
Mouse | MCA205 | ++ | – | +++ | – |
WOP | – | – | +++ | – | |
LOK | ++ | – | +++ | – | |
Rat | 208F | – | – | ++ | – |
Hamster | BHK-21 | – | – | + | – |
CHO | – | – | – | – | |
Dog | MDCK | – | +++ | – | – |
Cat | G355-5 | – | – | +++ | – |
Monkey | VERO | ++ | – | +++ | – |
Human | TE671 | + | – | ++ | – |
293T | +++ | – | + | – | |
HeLa | – | – | + | – |
Experimental conditions were the same as in Fig. 6, with the hyperfusogenic mutant amphotropic MLV envelope (A-Rless) used as a reference. Fusion indices were determined as indicated in Materials and Methods, with the following scale: –, <5; +, 5–20; ++, 20–70; +++, >70.