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Bony covering of critical size calvarial defects in the rat. The ability of TG-BMP2 and TG-BMP-2/BMP-7 in fibrin matrices to promote healing was examined in 8 mm defects in the rat, one per animal (n ≥ 5 for each group). The area of the defect covered with calcified tissue after 35 days of healing with standard errors is shown along with µCT top views (lower panel). * indicates significance with a p < 0.05.
