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Sequence diversity in GATA-binding FOG ZnFs. (A) The GATA-FOG structure showing the position of A225dFOG (Left), and the likely position of the valine side chain that replaces A225 in a complex formed between NF and mFOG-F6 (Right). (B) Position of the S218 side chain and the two nearby glutamates from NF (Left). (Right) The likely position of the arginine side chain that would replace S218 in a NF/mFOG-F1 complex.
