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. 2005 Jan 12;102(3):808–813. doi: 10.1073/pnas.0408962102

Fig. 3.

Fig. 3.

Cardiac CK flux is significantly decreased in human CHF. (a) Myocardial PCr/ATP. (b) PCr concentration ([PCr]) (μmol/g of wet weight). (c) ATP concentration ([ATP]) (μmol/g of wet weight). (d) CK forward rate constant, kfor (sec-1). (e) ATP synthesis through CK (μmol/g of wet weight per sec), for normal subjects (gray bars) and patients with heart failure (black bars). Note that the reduction in CK flux with heart failure is disproportionate to the reduction in metabolite levels. *, P = 0.03; †, P < 0.0005; §, P < 0.0005.