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. 2005 Jan 12;102(3):519–520. doi: 10.1073/pnas.0408858102

Fig. 1.

Fig. 1.

Diversity of natural products by means of biocombinatorial chemistry. Initially, biochemical modification of a scaffold results in a small number of structurally distinct compounds (C1, C2, and C3), followed by the production of more complex and unique compounds (C1a, C1b, C1c, etc.).